Diagnosis and treatment of primary biliary cholangitis

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Medical treatment of primary biliary cirrhosis and primary sclerosing cholangitis.

Treatment of primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) with ursodeoxycholic acid (UDCA) has been in common use since 1985. In PBC, treatment with UDCA improves laboratory data, liver histology, enables a longer transplantation-free interval and prolongs disease survival. Because UDCA is unable to cure the disease newer drugs or combination therapies are still need...

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Primary sclerosing cholangitis and primary biliary cirrhosis.

Preview Although primary sclerosing cholangitis occurs most often in middle-aged or younger men and primary biliary cirrhosis in middle-aged or older women, the diseases have some traits in common-unfortunate ones. In both diseases, the cause is unknown, and liver transplantation is the only known effective therapy for advanced cases. Dr Fennerty discusses trials of medical treatments used in a...

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ژورنال

عنوان ژورنال: United European Gastroenterology Journal

سال: 2020

ISSN: 2050-6406,2050-6414

DOI: 10.1177/2050640620919585